Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1995-03-02
1997-07-01
Schwadron, Ronald B.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435 71, 435 792, 435 793, 435342, 4353201, 4352523, 43525411, 435 72, 43525233, 435 795, 435325, 436811, 436503, 436536, 530822, 530350, 5303886, 5303895, 5303884, 530809, 536 237, G01N 33569, C07H 2104, C07K 1444, C07K 1620
Patent
active
056437374
ABSTRACT:
The present invention relates to a purified and isolated merozoite protein which is a specific indicator of infection by Babesia equi (B. equi) in horses. This protein contains a conserved region found in all strains of B. equi. It has a molecular weight of approximately 28 KDa and has been successfully purified and sequenced. The isolated and purified merozoite protein is used to prepare antibodies which can then be used in a competitive inhibition enzyme linked immunosorbent assay for the diagnosis of B. equi infection in horses.
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Knowles et al., J. Clin. Microbiol., 29: 2056-2058, 1991.
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Knowles et al., Inf. and Imm., vol. 59, No. 7, 2412-17, 1991.
Posnett et al., Molecular and Biochemical Parasitology, vol. 34 (1989), pp. 75-78' "Repetitive DNA Probes for the Detection of Babesia equi".
Knowles, Jr. Donald P.
Perryman Lance E.
Fado John D.
Lipovsky Joseph A.
Schwadron Ronald B.
Silverstein M. Howard
The United States of America as represented by the Secretary of
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