Phenyl, trihalomethyl or heteroaryl sulfoxides having a latent a

Details Phenyl, trihalomethyl or heteroaryl sulfoxides having a latent a Phenyl, trihalomethyl or heteroaryl sulfoxides having a latent a

1983-02-25

1985-12-10

Hollrah, Glennon H.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Radical -xh acid, or anhydride, acid halide or salt thereof...

514532, 514538, 514649, 514522, 260465D, 260465E, 544298, 544316, 544318, 544319, 544408, 546294, 548182, 548186, 548225, 548228, 548229, 548237, 549 65, 549 66, 560 11, 560 12, 560 17, 562429, 562430, 564440, 564503, 564341, 564509, 564510, 568 24, 568 25, A61K 3110, C07C14708

Patent

active

045580715

ABSTRACT:
Organic sulfoxides having a latent allyl group bound to the sulfur are enzyme inhibitors of the suicide or K.sub.cat type.

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patent: 4332813 (1982-06-01), Firestone
patent: 4342758 (1982-08-01), Firestone
Walsh, "Horizons Biochem. Biophys.", vol. 3, 1977, pp. 36-81.
Mislow, et al., J. Amer. Chem. Soc., vol. 90, 1968, pp. 4869-4876.
Mislow et al., J. Amer. Chem. Soc., vol. 92, 1970, pp. 2100-2104.
Evans, et al., J. Amer. Chem. Soc., vol. 94, 1972, pp. 3672-3674.

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