Steroid derivatives and their use in radioimmunoassays

Details Steroid derivatives and their use in radioimmunoassays Steroid derivatives and their use in radioimmunoassays

1978-05-22

1982-04-06

Roberts, Elbert L.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2603974, 26039747, 2603973, 26023955D, 23920, C07J 700

Patent

active

043235115

ABSTRACT:
Radiolabeled steroid derivatives having the formula ##STR1## wherein St is a 6-dehydro derivative of a 3-oxo-4,5-dehydro steroid intended for radioimmunoassay, said steroid being saturated in the 1,2-position; R is hydrogen or alkyl of 1 to 3 carbon atoms; n is 0, 1, 2, 3 or 4; and the asterisk (*) indicates tagging with a radioisotope, are useful as tracers in radioimmunoassays. The unlabeled analogs can be coupled with an immunogenic carrier and used to induce antibody formation in animals.

REFERENCES:
Smith et al., J.A.C.S., vol. 72, (1954) p. 1877.
Smith et al., J. Org. Chem., vol. 26, (1961) p. 3856.

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