Nitro-substituted dihydropyrroles and tetrahydropyridines, compo

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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424274, 424275, 424285, 546189, 546209, 546193, 548517, 548518, 548565, 548570, 548527, C07D20722, C07D21172, A61K 3144, A61K 3140

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044056249

ABSTRACT:
2,3-Unsaturated nitrogen-containing heterocyclic compounds with a 3-nitro group and a 2-heterocyclyl alkylamino group. The alkyl group of 2-position substituents is preferably interrupted by sulfur or oxygen. The compounds of the invention are preferably dihydropyrroles or tetrahydropyrridines or pyrimidines. The compounds of the invention are histamine H.sub.2 -receptor antagonists.

REFERENCES:
patent: 3518251 (1970-06-01), Gatzi
patent: 4128658 (1978-12-01), Price et al.
patent: 4238493 (1980-12-01), Roantree
patent: 4248873 (1981-02-01), Bossert et al.
patent: 4297498 (1981-10-01), Lawson et al.

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