Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acids and salts thereof
Patent
1995-03-07
1996-10-08
Geist, Gary
Organic compounds -- part of the class 532-570 series
Organic compounds
Carboxylic acids and salts thereof
562405, 562496, 562605, C07B 5300
Patent
active
055632955
ABSTRACT:
A process for the production of an optically active carboxylic acid (I), which comprises subjecting an olefinic carboxylic acid (II) to asymmetric hydrogenation using a complex as a catalyst consisting of an optically active phosphine (III) and a ruthenium compound.
Complex of ##STR1## with a ruthenium compound ##STR2## According to the process of the present invention, optically active carboxylic acids can be produced with high yield.
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Tetrahedron Letters, vol. 32, No. 49, pp. 7283-7286 (1991).
Journal of the Chemical Society, Perkin Trans., pp. 2309-2322 (1994).
Kumobayashi Hidenori
Matsumura Kazuhiko
Sayo Noboru
Takaya Hidemasa
Zhang Xiaoyong
Frazier Barbara S.
Geist Gary
Takasago International Corporation
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