Substituted imidazole derivatives useful as antihypertensive or

Details Substituted imidazole derivatives useful as antihypertensive or Substituted imidazole derivatives useful as antihypertensive or

1988-01-11

1989-05-02

Lee, Mary C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514397, 514400, 548336, 548342, 548345, A61K 31415, C07D23364

Patent

active

048268640

ABSTRACT:
Substituted imidazoles of the formula ##STR1## wherein R.sub.1 is H, an alkyl of 1 to 4 carbon atoms or --CH.sub.2 OH; R.sub.2 is H or CH.sub.3 ; R.sub.3 is ##STR2## and R.sub.4 is H; R.sub.5, R.sub.6 and R.sub.7 which can be the same or different, are H, --CH.sub.3 , --CH.sub.2 CH.sub.3, halogen, OH or --OCH.sub.3, or R.sub.5 is hydrogen and R.sub.6 and R.sub.7 together form an --O--CH.sub.2 --O--bridge between two adjacent carbon atoms in the phenyl group; provided that

REFERENCES:
patent: 2946804 (1960-07-01), Zaugg et al.
patent: 4213994 (1980-07-01), Gebert et al.

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