Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1993-03-05
1994-10-04
Cintins, Marianne M.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514647, A61K 31485
Patent
active
053526830
ABSTRACT:
Chronic pain is alleviated in a mammal suffering therefrom by administering to the mammal a chronic pain alleviating amount of a nontoxic N-methyl-D-aspartate receptor antagonist such as dextromethorphan, dextrorphan, ketamine or pharmaceutically acceptable salt thereof, alone or in combination with a local anesthetic and optionally in sustained release dosage form.
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Hayes et al., "Pretreatment with gangiolsides reduces abnormal nociceptive responses associated with a rodent peripheral mononeuropathy", Pain, 48 (1992) 391-396.
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Lyle John W.
Mao Jianren
Mayer David J.
Price Donald D.
Cintins Marianne M.
Jarvis William R. A.
Virginia Commonwealth University Medical College of Virginia
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