Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1975-11-20
1978-03-21
Gallagher, R.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
260287P, A61K 3147, C07D21506
Patent
active
040804569
ABSTRACT:
Diacylapomorphines of the formula ##STR1## wherein R.sub.1 and R.sub.2 are both acyl of 1-17 carbons are symptomatically effective agents in the treatment of motor disorders of the type associated with a dopamine deficiency of the extrapyramidal system of the central nervous system, e.g. Parkinson's disease. Pharmaceutical compositions containing these compounds as an active ingredient are described, as well as new compunds of the above formula wherein R.sub.1 and R.sub.2 are formyl or acyl of 3-17 carbon atoms.
REFERENCES:
patent: 3717639 (1973-02-01), Neumeyer
patent: 3717643 (1973-02-01), Archer
Lecomte et al., "Chemical Abstracts," vol. 58, 6104d, (1962).
Ibid. Janssen et al., vol. 55, 8659f, (1960).
Cannon et al., "J. Pharm. Sci.," 52, (11), 1112-1113, (1963).
Dictionary of Organic Compounds, Oxford Press (1965).
Horowski Reinhard
Kehr Wolfgang
Palenschat Dieter
Paschelke Gert
Schmiechen Ralph
Gallagher R.
Schering Aktiengesellschaft
Wheeler David E.
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