Process for producing 20-dihydro-20-deoxy-23-demycinosyltylosin

Details Process for producing 20-dihydro-20-deoxy-23-demycinosyltylosin Process for producing 20-dihydro-20-deoxy-23-demycinosyltylosin

1980-11-10

1981-12-08

Shapiro, Lionel M.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound containing saccharide radical

435253, 435896, C12P 1962, C12N 120, C12R 154

Patent

active

043048560

ABSTRACT:
20-Dihydro-20-deoxy-23-demycinosyltylosin (DH-DO-DMT), 20-dihydro-20-deoxy-5-O-mycaminosyltylonolide (DH-DO-OMT), specified acyl ester derivatives, and their acid addition salts are useful intermediates and antibacterial agents. Methods of preparing DH-DO-DMT and DH-DO-OMT by fermentation of Streptomyces fradiae and the microorganism S. fradiae ATCC 31733 are included.

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Chemical Abstract 93: 68663u (1980) Abstr. of Japan Kokai 80 43,0183.

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