Preparation of 4-methyl-5-chloromethyl-imidazole

Details Preparation of 4-methyl-5-chloromethyl-imidazole Preparation of 4-methyl-5-chloromethyl-imidazole

1978-12-29

1980-07-08

Trousof, Natalie

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D23364

Patent

active

042118751

ABSTRACT:
4-Methyl-5-chloromethyl-imidazole is prepared in the form of its hydrochloride by direct chloromethylation of 4-methyl-imidazole, thus becoming readily available industrially as an intermediate.

REFERENCES:
patent: 4104473 (1978-08-01), Sawa et al.
Grindley et al. J. Chem. Soc., 1927, pp. 3128-3136.
Hofmann Imidazole and Its Derivatives Part I pp. 99-100 N.Y., Interscience, 1953.
Noller Chemistry of Organic Compounds 2nd ed. p. 102 Philadelphia, Saunders, 1958.
Windaus Berichte (Deutsche Chem. Gesellschaft) 1909, vol. 42, pp. 758-763.

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