Chemical apparatus and process disinfecting – deodorizing – preser – Analyzer – structured indicator – or manipulative laboratory... – Calorimeter
Patent
1998-03-05
2000-01-18
Warden, Jill
Chemical apparatus and process disinfecting, deodorizing, preser
Analyzer, structured indicator, or manipulative laboratory...
Calorimeter
422 681, 422102, B01L 300, G01N 2100
Patent
active
060155310
DESCRIPTION:
BRIEF SUMMARY
The present invention relates to the analysis of one or more different liquid samples, with the aim of identifying, detecting and/or quantifying one or more analytes in it or them, using any analysis process, simple or complex, involving one or more different reagents, depending on the chemical, biochemical, biological or physical nature of the analyte or analytes being investigated.
The principle techniques defined and described below are not limited to a particular analyte, this generic term denoting both a composition, a compound and any chemical, biochemical or biological species or other entities, the only required condition being that the analyte is distributed as a suspension or solution in the initial liquid sample which is to be analyzed. In particular, the analysis process employed may be carried out in homogeneous, heterogeneous or mixed forms.
By way of non-limiting example, the present invention will nonetheless be illustrated with reference to the biological analysis of one or more ligands which, in order to be detected and/or quantified, require the use of one or more anti-ligands. The term "ligand" is intended to mean any biological species, for example an antigen, an antibody, a nucleic acid, a nucleic acid fragment or an oligonucleotide which can combine with an anti-ligand. An example of an application of the analysis techniques described below therefore relates to immuno-assays, irrespective of their format, for example by direct analysis or by competition. Of course, in the field of biology, the analysis techniques described below are nonetheless applied in the same way to the detection and/or quantification of a nucleic material or nucleotides.
In the field of biological analysis in particular, and as disposable or single-use products, analysis devices or cards are currently manufactured and available which generally comprise a body which is in the form of a plate and in which the following are arranged or formed: respectively different reagents and each designed to receive a share or aliquot, treated in each said operating compartment, of the initial liquid sample; with respect to one another and each communicating on one side with the introduction orifice and on the other side with an operating compartment.
With an analysis card of this type, the internal volume of which, consisting of the aforementioned elements, has been evacuated or depressurized beforehand, the initial liquid sample to be analyzed is introduced through the introduction orifice, by means of which the liquid in the sample is introduced and distributed, without other intervention, in the various operating compartments. The analysis card is then sealed at its introduction orifice, then subjected to various treatments, in particular incubation, to develop the reactions particular to the analysis process adopted in the various operating compartments, respectively. Lastly, the detection and/or quantification of the reaction products, for example by optical means, in the various operating compartments gives a set of qualitative and/or quantitative data allowing an analysis result to be expressed.
As mentioned above, the various steps or sequences required by the analysis, once the analysis card has been sealed, are generally implemented automatically in suitable analysis equipment, controlled or driven or, in particular, programmed in order to run the required operations automatically.
The above description shows that an analysis card of this type constitutes to some extent a passive component, insofar as it is no longer possible to move a given initial liquid sample, or a treated liquid sample, from one operating compartment to another, in order for any treatment process required for determination of the analyte to be carried out within the same analysis card.
According to document EP-A-0,339,277, an analysis card has been described which constitutes an active component, insofar as its arrangement makes it possible to move any liquid sample from one location in the card to another. To this end, the proposed analysis de
REFERENCES:
patent: 3690836 (1972-09-01), Buissiere et al.
patent: 4294931 (1981-10-01), Levein et al.
patent: 4985204 (1991-01-01), Klose et al.
patent: 5698395 (1997-12-01), Ritterband et al.
Cleuziat Philippe
Colin Bruno
Jaravel Cecile
Bio Merieux
Cannell Kevin P.
Warden Jill
LandOfFree
Single-use analysis card comprising a liquid flow duct does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Single-use analysis card comprising a liquid flow duct, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Single-use analysis card comprising a liquid flow duct will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-560952