Cytoplasmic antiproteinase-2 and cytoplasmic antiproteinase-3 an

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues

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435 692, C07K 1481

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active

057476454

ABSTRACT:
Cytoplasmic Antiproteinase-2 and Cytoplasmic Antiproteinase-3 nucleic acids and serine protease inhibitor proteins encoded thereby are useful in the purification of proteins and in the treatment of inflammatory diseases and diseases involving apoptosis.

REFERENCES:
patent: 5578705 (1996-11-01), Sprecher
Carrell et al., "The Serpins: Evolution and Adaptation in a Family of Protease Inhibitors," Cold Spring Harbor Symposia on Quantitative Biology, vol. LII, Cold Spring Harbor Laboratory, pp. 527-535 (1987).
Langer, "New Methods of Drug Delivery" Science 249:1527-1533 (Sep., 1990).
Deutscher, "Maintaining Protein Stability" Meths. Enzymol. 182:83-89 (1990).
Carrell et al., "Mobile Reactive Centre of Serpins and the Control of Thrombosis" Nature 353: 576-578 (Oct., 1991).
Ray et al., "Viral Inhibition of Inflammation: Cowpox Virus Encodes an Inhibitor of the Interleukin-1.beta. Converting Enzyme," Cell 69:597-604 (May, 1992).
Remold-O'Donnell et al., "Sequence and Molecular Characterization of Human Monocyte/Neutrophil Elastase Inhibitor," Proc. Natl. Acad. Sci. USA, 89:5635-5639 (Jun., 1992).
Lomas et al., "Inhibition of Plasmin, Urokinase, Tissue Plasminogen Activator, and C.sub.1s by a Myxoma Virus Serine Proteinase Inhibitor" J. Biol. Chem. 268: 516-521 (Jan., 1993).
Remold-O'Donnell, "The Ovalbumin Family of Serpin Proteins" FEBS Letters 315: 105-108 (Jan., 1993).
Coughlin et al., "Cloning and Molecular Characterization of a Human Intracellular Serine Proteinase Inhibitor," Proc. Natl. Acad. Sci. USA, 90:9417-9421 (Oct., 1993).
Morgenstern et al., "Isolation and Characterization of an Intracellular Serine Proteinase Inhibitor from a Monkey Kidney Epithelia Cell Line", J. Biol. Chem. 268: 21560-21568 (Oct., 1993).
Miura et al., "Induction of Apoptosis in Fibroblasts by IL-1.beta.-Converting Enzyme, a Mammalian Homolog of the C. elegans Cell Death Gene ced-3," Cell 75: 653-660 (Nov., 1993).
Yuan et al., "The C. elegans Cell Death Gene ced-3 Encodes a Protein Similar to Mammalian Interleukin-1.beta.-Converting Enzyme" Cell 75: 641-652 (Nov., 1993).
Gagliardini et al., "Prevention of Vertebrate Neuronal Death by the crmA Gene," Science 263: 826-828 (Feb., 1994).
Potempa et al., "The Serpin Superfamily of Proteinase Inhibitors: Structure, Function, and Regulation" J. Biol. Chem. 269: 15957-15960 (Jun., 1994).
Wang et al., "Ich-1, an Ice/ced-3-Related Gene, Encodes Both Positive and Negative Regulators of Programmed Cell Death," Cell 78: 739-750 (Sep., 1994).
Morgenstern et al., "Complementary DNA Cloning and Kinetic Characterization of a Novel Intracellular Serine Proteinase Inhibitor: Mechanism of Action with Trypsin and Factor Xa as Model Proteinases," Biochem. 33:3432-3441 (1994).
Patston et al., "A Database of Recombinant Wild-type and Mutant Serpins" Thromb. Haemostas. 72:166-179 (1994).

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