2-Thiazolyl, isothiazolyl, oxazolyl and isoxazolyl alkylamino-3-

Details 2-Thiazolyl, isothiazolyl, oxazolyl and isoxazolyl alkylamino-3- 2-Thiazolyl, isothiazolyl, oxazolyl and isoxazolyl alkylamino-3-

1983-04-25

1985-06-25

Fan, Jane T.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514340, 514342, 514343, 514369, 514370, 514365, 514372, 514376, 514377, 514374, 514380, 546280, 546275, 546256, 546281, 548183, 548184, 548186, 548189, 548193, 548202, 548203, 548213, 548214, 548225, 548226, 548228, 548229, 548233, 548235, 548243, 548244, 548245, 548247, C07D41312, A61K 3144

Patent

active

045254770

ABSTRACT:
2,3-Unsaturated nitrogen-containing heterocyclic compounds with a 3-nitro group and a 2-heterocyclyl alkylamino group. The alkyl group of 2-position substituents is preferably interrupted by sulfur or oxygen. The compounds of the invention are preferably dihydropyrroles or tetrahydropyrridines or pyrimidines. The compounds of the invention are histamine H.sub.2 -receptor antagonists.

REFERENCES:
patent: 3932644 (1976-01-01), Durant et al.
patent: 3953460 (1976-04-01), Durant et al.
patent: 3980781 (1976-09-01), Snell et al.
patent: 4062863 (1977-12-01), Ganellin et al.
patent: 4128658 (1978-12-01), Price et al.
patent: 4166856 (1979-09-01), Durant et al.
patent: 4238493 (1980-12-01), Roantree et al.

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