2-Amino-6-biphenylacetic acids

Details 2-Amino-6-biphenylacetic acids 2-Amino-6-biphenylacetic acids

1980-07-02

1982-06-08

Trousof, Natalie

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant or stably-transformed bacterium encoding one or...

424309, 562456, 562457, 562452, 560 47, 560 45, 560 48, C07C101447, A61K 31195, A61K 31215

Patent

active

043339514

ABSTRACT:
Novel 2-amino-6-biphenylacetic acids, esters, and metal salts are provided of the formula: ##STR1## wherein R represents hydrogen or lower alkyl, R.sup.1 represents fluoro, chloro, bromo, lower-alkyl or amino; R.sup.2 represents lower-alkyl, lower-alkoxy, fluoro, chloro, bromo, amino or trifluoromethyl; n is 0-3 and m is 0-2, and the pharmaceutically acceptable salts thereof. The compounds exhibit muscle relaxant activity, and are also useful as anti-inflammatory agents.

REFERENCES:
patent: 3452079 (1969-06-01), Shen et al.
patent: 3457300 (1969-07-01), Dorn et al.
patent: 3624142 (1971-11-01), Shen et al.
patent: 3784704 (1974-01-01), Cohen et al.
patent: 3821268 (1974-06-01), Diamond et al.
patent: 3966978 (1976-06-01), Elenbogen et al.
patent: 4021479 (1977-05-01), Seeger et al.

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