Process for preparing substituted cyclic acetals of oxyacetaldeh

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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2603407, 2603409R, C07D31710, C07D31906, C07D32106

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active

042487870

ABSTRACT:
A process is described for the preparation of substituted oxyacetaldehydes and cyclic acetals thereof according to the reaction sequence: ##STR1## wherein R.sub.1 and R.sub.2, taken together form a lower alkylene group; wherein R.sub.3 is alkyl, alkenyl or alkadienyl and X is halogen selected from the group consisting of chlorine and bromine, the reaction (i) being carried out (1) using a "phase transfer agent" and (2) in a two phase system.

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Normant, H., Comptes Rendus l'Acad. Sciences 232 (1951), pp. 1942-1945.
Arctander, "Perfume and Flavor Chemicals", vol. 1, 1969, #688.
Arctander, "Perfume and Flavor Chemicals", vol. 1, 1969, #689.
Bedoukian, "Perfumery and Flavoring Synthetics", Elsevir Publishing Co., 2nd Revised Edition, 1967, p. 378.
Eastman Organic Chemicals Bulletin, vol. 48, #1, 1976, p. 2.
Freedman et al., Tetrahedron Letters, No. 38, pp. 3251-3254 (1975).

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