Mice lacking expression of osteoprotegerin

Multicellular living organisms and unmodified parts thereof and – Nonhuman animal – Transgenic nonhuman animal

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800 9, 800 3, 800 21, 800 22, 800 25, 4353201, 435325, 435455, 435463, C12N 500, C12N 1500, C12N 1509, C12N 1563

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active

060875550

ABSTRACT:
Disclosed is a mouse in which expression of the gene encoding Osteoprotegerin is suppressed. Also disclosed is a nucleic acid construct useful in preparing such a mouse, and a cell line containing such construct.

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