Process for producing purine derivatives

Details Process for producing purine derivatives Process for producing purine derivatives

1998-07-23

2000-07-11

Berch, Mark L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Chalcogen bonded directly to ring carbon of the purine ring...

544244, 544264, 544265, 544267, 544271, 544272, 544273, 544277, C07D47318, C07D47330, C07D47334, C07D47316, C07D47306

Patent

active

06087497&

ABSTRACT:
9-Substituted purine derivatives of formula (4) ##STR1## are prepared by debenzylating a compound of formula (3): ##STR2##

REFERENCES:
patent: 5336770 (1994-08-01), Shiragami et al.
patent: 5942617 (1999-08-01), Shiragami
Vel'kina, Chem. Abs. vol. 67, 64362k, 1967.
P. Brookes et al, The Preparation and Properties of Some Benzylated Nucleosides, J. Chem. Soc., pp. 2026-2028, Aug. 30, 1968.
G. Green et al, "Regiospecific Michael Additions With 2-Aminopurines", Tetrahedron Letters, Aug. 4, 1992, pp. 4609-4612, vol. 33, No. 32.
J. Jones et al, "Potential Purine Antagonists. XXX. Purine Betaines and Related Derivatives Prepared By Direct Methylation of the Simple Purines", Contribution of the Department of Chemistry, Arizona State University, Tempe, Arizona, Nov. 18, 1961, pp. 1914-1919, vol. 84.
C. Muller, "Formation of 7,9-Disubstituted Xanthinium Compounds Under Mild Conditions By Alkylation F Silylated Xanthines", Synthetic Communications, 1994, pp. 1311-1315, vol. 24, No. 9.

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