Stabilized vitamin C formulations

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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A61K 3134

Patent

active

060873930

ABSTRACT:
The invention features a method of stabilizing free 1-ascorbic acid from oxidation by dispersing the free 1-ascorbic acid in a mixed glycol carrier and a solution containing the ascorbic acid in the mixed glycol solution. The mixed glycol carrier contains a mixture of at least propylene glycol and butylene glycol, but may contain other glycols such as polyethylene glycol , and stabilizing and solubility assisting agents as well.

REFERENCES:
patent: 5002761 (1991-03-01), Mueller et al.
patent: 5035895 (1991-07-01), Shibusawa et al.
patent: 5140043 (1992-08-01), Darr et al.
patent: 5552446 (1996-09-01), Candau et al.
patent: 5587149 (1996-12-01), Punto et al.
patent: 5843411 (1998-12-01), Hernandez et al.
England et al., "The biochemical functions of ascorbic acid," Ann. Rev. Nutr., 6:365-406 (1986).

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