Pharmaceutical non inorganic saline solutions for endonasal admi

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

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530307, A61K 3823

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active

060873388

ABSTRACT:
The subject-matter of the invention are pharmaceutical non inorganic saline solutions for endonasal administration containing: (a) a calcitonin, preferably salmon or alternatively carbacalcitonin (elcatonin), or its pharmaceutically acceptable salts; characterized in that it further contains the organic excipients; (b) N-(methyl)-glucamine or glucamine; (c) tromethamine; (d) citric acid; and (e) polyvinylpyrrolidone ranging from K15 to K120. These are odorless and tasteless and thus have improved patient's compliance not having the undesirable secondary effects of known compositions as well as permit a complete and accurate analysis of the active principle and develop less degradation products during storage.

REFERENCES:
patent: 4690952 (1987-09-01), Kagatani et al.
patent: 5026825 (1991-06-01), Grebow et al.
patent: 5183802 (1993-02-01), Aliverti et al.
patent: 5571788 (1996-11-01), Arvinte et al.
patent: 5733569 (1998-03-01), Azria et al.
Sato et al., "Stabilization of Injection Solutions Containing [ASM 1,7] Callitonin" Caplus ABS # 1994:280287, Feb. 8, 1994.
Ogiso, "Topilar Solutions Containing Calcitonin as Absorption Accelerator" Caplus ABS # 1992:476537, 1992.
U.S. Pharmacopeia "Official Jan. 1, 1995" V. 23, NF18 (Defining "K-Value" for Povidone).
"Calcitonin (Salmon)" European Pharmacopoeia (1997) pp. 508-511, published in Europe.
Bruynzeel, DP et al. "Contact dermatitis to lauryl pyridinium chloride and benzoxonium chloride" Contact Dermatitis (1987) vol. 17, pp. 41-60, published in Europe.
Fisher, A. "Allergic Contact Dermatitis and Conjunctivitis from Benzalkonium Chloride" Cutis (May 1987) vol. 39, pp. 381-383.
Lee, KC et al. "Degradation of Synthetic Salmon Calcitonin in Aqueous Solution" Pharmaceutical Research (1992) vol. 9, No. 11, pp. 1521-1523.
Lemp, MA and LE Zimmerman. "Toxic Endothelial Degeneration in Ocular Surface Disease Treated with Topical Medications Containing Banzalkonium Chloride" American Journal of Ophthalmology, (Jun. 1988) vol. 105, pp. 670-673, published in US.
Chemical Abstracts 98: 204410s, Larsen et al., 1983.
Chemical Abstracts 118: 66873y, Sims et al., 1993.
Chemical Abstracts 118: 198207u, Santus et al., 1993.
Chemical Abstracts, vol. 117, No. 10, Sep. 7, 1992, Columbus, Ohio, US; Abstract No. 97319, Nogata, Yoshihiko et al.: "Aqueous Compositions Containing Calcitonins" XP002005905.
Database WPI, Section Ch., Week 9211, Derwent Publications Ltd., London, GB; Class B04, AN 92-85873, & JP,A,04 029 938 (Toyo Jozo KK), Jan. 31, 1992.
Patent Abstracts of Japan, vol. 16, No. 194 (C-938), May 11, 1992 & JP,A,04 029938 (Toyo Jozo Co Ltd.), Jan. 31, 1992.

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