Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1990-02-01
1992-01-14
Springer, David B.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
548492, 548494, C07D20912, A61K 31405
Patent
active
050811452
ABSTRACT:
Indole-2-alkanoic acids are disclosed. The compounds act as prostaglandin and thromboxane antagonists and are useful in treating asthma, inflammation, diarrhea, hypertension, angina, platelet aggregation, cerebral spasm, premature labor, spontaneous abortion and dismenorrhea and as cytoprotective agents.
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Walton, et al., J. Med. Chem., 8, 204 (1965).
E. Walton, et al., J. Med. Chem., 11, 1252 (1968).
Fortin Rejean
Gillard John W.
Guindon Yvan
Jones Thomas R.
Yoakim Christiane
DiPrima Joseph F.
Lopez Gabriel
Merck Frosst Canada Inc.
Springer David B.
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