Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1990-09-19
1992-01-14
Friedman, Stanley J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514422, 514425, A61U 3140, A61U 31445
Patent
active
050811304
ABSTRACT:
Compounds useful for the treatment of patients suffering from muscle spasms of the formula (I) ##STR1## in which R represents the radical ##STR2## in which R.sub.1, in any position on the phenyl nucleus, represents a linear, branched or cyclic alkyl, alkenyl or alkynyl, containing up to 8 carbon atoms, or the radical ##STR3## in which R.sub.2 and R.sub.3, identical or different each represents a hydrogen atom, a linear alkyl, alkenyl or alkynyl, containing up to 8 carbon atoms, or form together with the nitogen atom to which they are joined, a heterocyclic radical optionally containing another heteroatom, or NO.sub.2, or OR', R' representing hydrogen, a linear, branched or cyclic alkyl containing up to 8 carbon atoms, or aryl containing up to 14 carbon atoms, or an SR.sub.4 or S(O)R.sub.5 radical, R.sub.4 and R.sub.5 representing a linear, branched or cyclic alkyl, alkenyl or alkynyl, containing up to 8 carbon atoms, or R represents naphthyl, optionally substituted by an R.sub.1 radical, as defined above; also therapeutic compositions containing the same and method of use.
REFERENCES:
patent: 4217130 (1980-08-01), Tsuruta et al.
patent: 4833156 (1989-05-01), Sakakibara et al.
patent: 4999372 (1991-03-01), Regnier et al.
Chem. Abs. 77 (5):34303f, 1972, Shigezane et al. 3-(Acylamino)-2-pyrrolidinone derivatives.
Chem. Abs. 71(13): 61108d, 1969, Stamm. Aminoethylation with Aziridines VI 3-Alkoxycarbonyl-2-pyrrolidinone Compounds from a Ziridine Bases and Malonic Esters.
Chemical Abstracts 110:75307d (1989), Sakakibara et al.
Barzaghi Fernando
Fortin Michel
Galliani Giulio
Gorini Carlo
Toja Emilio
Friedman Stanley J.
Roussel Uclaf
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