Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Separation or purification
Patent
1990-10-15
1991-09-10
Nutter, Nathan M.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Separation or purification
530417, 210656, 515 541, 515 543, 515 5431, 515 5432, 515 544, 515 5445, A23J 100, C07K 300, C07K 1300, C07K 1500
Patent
active
050475134
ABSTRACT:
Metal chelate resins whose complexed nitrilotriacetic acid residues are bound to a carrier matrix via a spacer and which are suitable for metal chelate chromatography of proteins, especially those which contain neighboring histidines.
REFERENCES:
patent: 4569794 (1986-02-01), Smith et al.
Lonnerdal et al., "Metal Chelate Affinity Chromatography of Proteins", J. of App. Biochem. 4, 203-208 (1982), pp. 203-208.
Dobeli Heinz
Hochuli Frich
Epstein William H.
Gould George M.
Hoffmann-La Roche Inc.
Nutter Nathan M.
Tramaloni Dennis P.
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