DNA encoding HTNF variants exhibiting enhanced activity

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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4353201, 435 91, 536 27, 935 9, 935 11, 935 12, 935 13, C12P 2100, C12P 2102, C07H 1512

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active

050810219

ABSTRACT:
Novel DNA's encoding variants of TNF which comprise substitutions and/or deletions in the n-terminal portion of the TNF polypeptide resulting in enhanced cytotoxic activity are taught.

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