Methods for predicting drug response

Details Methods for predicting drug response Methods for predicting drug response

1998-07-27

2000-07-11

Leary, Louise N.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

435 14, 435975, 530303, 530356, 530350, 514 3, 514 21, 514 12, 552502, C12Q 100, C12Q 154, G01N 3353

Patent

active

060870907

ABSTRACT:
Methods are provided for formulating models for predicting whether subjects will respond to a particular drug or treatment regimen. Biochemical profiles are obtained (by measuring a variety or biochemical parameters) for a test group before and after treatment with the drug or regimen. These values are used formulate a specific predictive method for the particular drug or treatment regimen. The predictive measurement is then used with biochemical parameters obtained from a subject to predict whether that subject will respond to the particular drug or treatment regimen. The predictive methods may also be used to determine the equivalence of different dosages of a drug.

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