Photodynamic therapy of glioma or mammary carcinoma using seleno

Details Photodynamic therapy of glioma or mammary carcinoma using seleno Photodynamic therapy of glioma or mammary carcinoma using seleno

1988-10-24

1991-09-10

Waddell, Frederick E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514459, 514460, 514180, A61K 31095, A61K 3135, A61K 3156

Patent

active

050474197

ABSTRACT:
There are disclosed pyrylium salts and a method of using them medicinally in photodynamic therapy for increasing the survival time of animals affected with glioma or mammary carcinoma. The salts are seleno- or telluropyrylium compounds having a singlet oxygen quantum efficiency of at least 0.005 when exposed as described at wavelengths between about 650 and 1000 nanometers.

REFERENCES:
patent: 4365017 (1982-12-01), Detty et al.
patent: 4584258 (1986-04-01), Detty et al.
J. Clin. Oncology, vol. 6, p. 380 (1988).

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