Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1989-02-01
1991-09-10
Chan, Nicky
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
549375, 549373, 549370, 549359, 549349, 548253, 548252, 546175, 546174, 546172, 546159, 546155, 546153, 546146, 546147, 546143, 546142, 546141, 514459, 514455, 514454, 514452, 514450, 514382, 514314, 514313, 514312, 514310, 514309, A61K 31335, A61K 3134, C07D31906, C07D25704
Patent
active
050474120
ABSTRACT:
The invention describes novel (2-styryl-, 2-naphthyl- and 2-phenethyl-4-o-hydroxyphenyl-1,3-dioxan-5-yl)alkenoic acids and related tetrazoles and sulphonamides, of the formula I wherein Q completes a benzene or pyridine ring, Y is vinylene, Z is carboxy, 1(H)-tetrazol-5-yl or a group of the formula --CO.NHSO.sub.2 R.sup.6, and R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, A.sup.1, A.sup.2, n and m have the meanings defined in the specification, and pharmaceutically acceptable salts thereof, for use in conjunction with their pharmaceutical compositions in treating certain pulmonary and/or vascular disorders. The invention also describes various processes and intermediates for the manufacture of the novel compounds.
REFERENCES:
patent: 4567197 (1986-01-01), Brewster et al.
Brown George R.
Smithers Michael J.
Chan Nicky
Imperial Chemical Industries plc
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