Induction of immunological tolerance

Details Induction of immunological tolerance Induction of immunological tolerance

1978-09-25

1980-09-16

Danison, Walter C.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

2601127, 424 12, 424 78, 424 88, 424 91, 528328, C08L 8900, C08L 7704, A61K 3900, A61K 3726

Patent

active

042229073

ABSTRACT:
Immunosuppressive agents which are conjugates of an antigen linked to a D glutamic acid:D-lysine copolymer are disclosed. Also disclosed are methods of preparing the conjugates and therapeutic methods for inducing immunological tolerance to antigens.

REFERENCES:
patent: 3794630 (1974-02-01), Mullan et al.
Nossal et al., J. of Exp'l. Med., vol. 138 (1973) pp. 312-317. _
Eshar et al., J. Immunol., vol. 114, No. 2 (1975) pp. 872-876. _
Chiorazzi et al., Proc. Natl. Acad. Sci., U.S.A., vol. 73, No. 6 (1976) pp. 2091-2095. _
Bitter-Suermann et al., Chem. Abst's., vol. 83:129,895p (1975). _
Mosier et al., Chem. Abst's., vol. 83:191,237d (1975). _

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