Microfabricated structures for facilitating fluid introduction i

Details Microfabricated structures for facilitating fluid introduction i Microfabricated structures for facilitating fluid introduction i

1999-03-23

2000-07-11

Warden, Jill

Chemical apparatus and process disinfecting, deodorizing, preser

Control element responsive to a sensed operating condition

436180, 204600, 204601, 204604, B01L 302

Patent

active

060868252

ABSTRACT:
Fluid introduction is facilitated through the use of a port which extends entirely through a microfluidic substrate. Capillary forces can be used to retain the fluid within the port, and a series of samples or other fluids may be introduced through a single port by sequentially blowing the fluid out through the substrate and replacing the removed fluid with an alternate fluid, or by displacing the fluid in part with additional fluid. In another aspect, microfluidic substrates have channels which varying in cross-sectional dimension so that capillary action spreads a fluid only within a limited portion of the channel network. In yet another aspect, the introduction ports may include a multiplicity of very small channels leading from the port to a fluid channel, so as to filter out particles or other contaminants which might otherwise block the channel at the junction between the channel and the introduction port.

REFERENCES:
patent: 3799742 (1974-03-01), Coleman
patent: 4225410 (1980-09-01), Pace
patent: 4517089 (1985-05-01), Arnaud
patent: 4686041 (1987-08-01), Van den Berg et al.
patent: 4726900 (1988-02-01), Keskinen et al.
patent: 4795560 (1989-01-01), Chupka et al.
patent: 4908112 (1990-03-01), Pace
patent: 4963498 (1990-10-01), Hillman et al.
patent: 4978503 (1990-12-01), Shanks et al.
patent: 5108704 (1992-04-01), Bowers et al.
patent: 5147606 (1992-09-01), Charlton et al.
patent: 5180480 (1993-01-01), Manz
patent: 5250263 (1993-10-01), Manz
patent: 5262128 (1993-11-01), Leighton
patent: 5296375 (1994-03-01), Kricka et al.
patent: 5304487 (1994-04-01), Wilding et al.
patent: 5376252 (1994-12-01), Ekstrom et al.
patent: 5427663 (1995-06-01), Austin
patent: 5427946 (1995-06-01), Kricka et al.
patent: 5429734 (1995-07-01), Gajar et al.
patent: 5443890 (1995-08-01), Ohman
patent: 5486335 (1996-01-01), Wilding et al.
patent: 5500071 (1996-03-01), Kaltenbach et al.
patent: 5503803 (1996-04-01), Brown
patent: 5513757 (1996-05-01), Papetti
patent: 5560811 (1996-10-01), Brigges
patent: 5571410 (1996-11-01), Swedberg et al.
patent: 5603351 (1997-02-01), Cherukuri et al.
patent: 5635358 (1997-06-01), Wilding et al.
patent: 5756050 (1998-05-01), Ershow et al.
patent: 5766193 (1998-06-01), Millner
patent: 5770029 (1998-06-01), Nelson et al.
patent: 5792354 (1998-08-01), Aksberg
patent: 5882930 (1999-03-01), Baier
patent: 5885470 (1999-03-01), Parce et al.
patent: 5904824 (1999-05-01), Oh
Adam T. Woolley et al, "Ultra-High-speed DNA fragment separations using microfabricated capillary array electrophoresis chips" Proceedings of the National Academy of Science, USA vol. 91 (1994) 11348-11352, No month available.

Affiliated with

Also associated with

Rating

Microfabricated structures for facilitating fluid introduction i does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Microfabricated structures for facilitating fluid introduction i, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Microfabricated structures for facilitating fluid introduction i will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-538904