Method for preparing 3-amino-2-chloro-4-alkylpyridines

Details Method for preparing 3-amino-2-chloro-4-alkylpyridines Method for preparing 3-amino-2-chloro-4-alkylpyridines

1991-06-11

1993-04-06

Ivy, C. Warren

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546311, C07D21373

Patent

active

052005224

ABSTRACT:
A process for the preparation of a 3-amino-2-chloro-4-alkylpyridine of the formula: ##STR1## wherein R is alkyl of from one to three carbon atoms, an intermediate in the preparation of certain 5,11-dihydro-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepine compounds useful in the prevention and treatment of HIV infection.

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Lounasmaa, et al., "Tetrahedron", vol. 33, 1977, pp. 113-117.
Bobbitt, et al., J. Org. Chem. vol. 25, 1960, pp. 560-564.
Morisawa, et al., "J. Med. Chem.", vol. 21, No. 2, 1978, pp. 194-199.
Schickh, et al., "Berichte der Deutschen Chemischen", Nr. 12, 1936, p. 2605.
Schmitz, et al., "Archiv. d. Pharmazic", vol. 308, 1975, pp. 433-437.

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