Biomolecules covalently immobilized with a high bound specific b

Details Biomolecules covalently immobilized with a high bound specific b Biomolecules covalently immobilized with a high bound specific b

1990-11-05

1993-04-06

Page, Thurman K.

Synthetic resins or natural rubbers -- part of the class 520 ser

Synthetic resins

Mixing of two or more solid polymers; mixing of solid...

424 7808, 424 7822, 424 7823, 424 7828, 424 7829, C08F 2610, A61K 31395

Patent

active

052004716

ABSTRACT:
A biologically active adduct support, prepared from an azlactone-functional polymeric support and biomolecules covalently immobilized thereon, is disclosed. The biomolecules are covalently immobilized in the presence of polyanionic salt using a method which achieves both high density and optimized bound specific biological activity. Preferably, the immobilization occurs in the presence of an azlactone quencher.

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