Balloon catheter for photodynamic therapy

Surgery – Means for introducing or removing material from body for... – Treating material introduced into or removed from body...

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604 20, 604500, 606192, 607 88, 607 92, A61M 2900

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06086558&

ABSTRACT:
The present invention provides improved balloon catheter apparatuses for use in therapies requiring delivery of uniform light to a treatment area. The improved apparatus comprises a balloon having a defined treatment window where the window is delineated using a reflective material. The apparatus may further comprise a fiber optic cable that terminates in a diffusion tip where the diffusion tip is longer than the treatment window. The present invention further provides improved therapeutic methods that use the improved balloon catheters of the present invention.

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Marcus, S.L., "Photodynamic Therapy of Human Cancer: Clinical Status, Potential, and Needs," Future Directions and Applications in Photodynamic Therapy/SPIE Institute Series vol. IS 6:5-56 (1990).
Nseyo, U.O. et al., "Whole Bladder Photodynamic Therapy: Critical Review of Present-Day Technology and Rationale for Development of Intravesical Laser Catheter and Monitoring System," Urology 36(5):398-402 (Nov. 1990).
Overholt, B.F. et al., "Photodynamic Therapy in Barrett's Esophagus: Reduction of Specialized Mucosa, Ablation of Dysplasia, and Treatment of Superficial Esophageal Cancer," Seminars in Surgical Oncology 11(5):372-376 (Sep./Oct. 1995).
Overholt, B.F. et al., "Photodynamic Therapy for Esophageal Cancer Using a 180.degree. Windowed Esphageal Balloon," Lasers in Surgery and Medicine 14(1):27-33 (1994).
Panjehpour, M. et al., "Centering Balloon to Improve Esophageal Photodynamic Therapy," Lasers in Surgery and Medicine 12(6):631-638 (1992) .

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