Debridement of bodily cavities using debridement fluids

Drug – bio-affecting and body treating compositions – Designated organic nonactive ingredient containing other... – Aftertreated solid synthetic organic polymer

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424 5, A61K 4700

Patent

active

052004309

ABSTRACT:
Foreign substances may be removed from a mammalian body cavity containing an aqueous phase by injecting into the cavity a water-immiscible, optically clear, biocompatible debridement fluid to at least partially displace the aqueous phase, and removing the aqueous phase and the foreign substances. In addition, a method is provided for visualizing a transparent foreign substance in a mammalian body cavity using a water-immiscible, optically clear, biocompatible fluid having a refractive index different from that of water. The debridement fluid may also be used to reposition desirable substances, such as a lens in an ocular cavity, or to remove a secondary membrane from a cavity lining or structure. Preferably, a liquid heavier than water, such as a perfluorocarbon liquid, is used as the debridement fluid.

REFERENCES:
patent: 4490351 (1984-12-01), Clark, Jr.
Nabih, M., et al., "Experimental Evaluation of Perfluorophenanthrene as a High Specific Gravity Vitreous Substitute: A Preliminary Report," Ophthalmic Surgery, 20(4):286-93 (1989).
Chang, S., et al., "Experimental Vitreous Replacement With Perfluorotributylamine," Am. J. Ophth., 103:29-37 (1987).

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