Process for preparation of copolymer

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing oxygen-containing organic compound

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435247, 435822, 435829, 435831, C12P 762, C12R 105, C08G 6306

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active

052003329

ABSTRACT:
Disclosed is a process for the preparation of a copolymer, which comprises propagating cells of a bacterium having a capacity of producing poly-3-hydroxybutyrate mainly at a former stage, synthesizing and accumulating in the cells a copolymer comprising D-3-hydroxybutyrate and D-3-hydroxyvalerate by contacting the bacterium with a mixture of a carbon source utilizable by the bacterium and a primary alcohol having 3 to 7 carbon atoms, or with a primary alcohol having 3 to 7 carbon atoms, at a latter stage, and recovering the copolymer from the cells. According to this process, a copolymer comprising D-3-hydroxybutyrate and D-3-hydroxyvalerate can be manufactured in a large quantity at a low cost.

REFERENCES:
"Systematic Bacteriology" Bergey's Manual vol. I pp. 140-142, 235-236, 325, 399 (1984) Krieg Editor Publisher Williams & Wilkens.
Bergeys Manual Systematic Bacteriology vol. 3, Staley Editor vol. III p. 1895 (1989) Publisher Williams & Wilkens.
"Internat. Journal Systematic Bact." Apr. 1984, pp. 188-201, vol. 34, No. 2, Urakami et al.
Internat. Jour. Syst. Bact. Apr. 1985, p. 209, vol. 35, No. 2.
Biotech Abs. 91-10051 EP-431883 (Jun. 1991) ICI.
Biotech Abs. 87-02762 EP-204442 (Dec. 1986) ICI.

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