Materials and methods for species-specific detection of mycobact

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

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435 911, 435 912, 536 243, 536 2432, C12Q 168, C12P 1934, C07H 2104

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057472599

ABSTRACT:
A newly-identified M. kansasii DNA sequence is described and designated KATS1. This sequence is highly M. kansasii-specific in nucleic acid hybridization assays and is useful for detecting both typical and atypical strains. KATS1 and segments of the KATS1 sequence are useful for species detection of M. kansasii in hybridization or nucleic acid amplification assays with 100% specificity and no cross-reactivity to non-M. kansasii species.

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