Radiosensitizing nitrobenzoic acid amide derivatives

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...

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564139, 564157, C07C10382, C07C10387, A61K 31165

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active

044748140

ABSTRACT:
Nitrobenzoic acid amide derivative represented by the formula ##STR1## wherein A is (CH.sub.2).sub.x NH(CH.sub.2).sub.y or (CH.sub.2).sub.x NH(CH.sub.2).sub.y NH(CH.sub.2).sub.z, n is 1 or 2, x, y and z are each 2 to 5, and pharmacologically acceptable acid salt thereof is an excellent radio-sensitizer.

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patent: 3499031 (1970-03-01), Smith et al.
patent: 4009208 (1977-02-01), Lesher
patent: 4058523 (1977-11-01), Mori et al.
Smithen et al., Radiation Sensitizer, pp. 22-38, (1982), ed. by Brady, Masson Publishing, (U.S.).
Stratford et al., Radiation Research 88, pp. 502-509, (1981).
Winkelmann et al., Arzneimittel-Forschung, 25, pp. 681-708, (1975).

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