Process for the production of human chorionic gonadotropin

Details Process for the production of human chorionic gonadotropin Process for the production of human chorionic gonadotropin

1981-08-07

1983-05-10

Rosen, Sam

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Using tissue cell culture to make a protein or polypeptide

435 68, 435 71, C12P 2102, C12P 2104, C12P 2100

Patent

active

043830366

ABSTRACT:
The present invention relates to a process for the production of human chorionic gonadotropin (hCG).
More precisely, the invention relates to a process for the mass production of hCG, comprising in vivo multiplication of human lymphoblastoid cells capable of producing hCG, and hCG production by the multiplied human lymphoblastoid cells.
The hCG production according to the invention is extremely higher, in terms of hCG production per cell, than that attained by conventional process using in vitro tissue culture; thus, hCG can be used in a sufficient amount in the prevention and treatment of human diseases.

REFERENCES:
patent: 4288546 (1981-09-01), Narasimhan et al.

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