Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1974-08-20
1976-03-30
Gallagher, Richard J.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
2602564C, 2602565R, 424251, C07D23942
Patent
active
039474410
ABSTRACT:
Cpmpounds of the class of 5-substituted and 5,6-disubstituted 2-amino-4-(hydroxyamino) and 2,4-bis-(hydroxyamino)pyrimidines and their pharmaceutically acceptable acid addition salts possess valuable biological properties, in particular antibacterial and antimalarial activity and potentiate the action of antibacterial sulphanilamide derivatives. Specific embodiments are 2-amino-4-(hydroxyamino)-5-(3,4,5-trimethoxybenzyl)-pyrimidine, and 2-amino-4-(hydroxyamino)-5-(p-chlorophenyl)-6-ethyl pyrimidine and its hydrochloride.
REFERENCES:
patent: 3513185 (1970-05-01), Cresswell et al.
Frei Jorg
Ilvespaa Atso
Schweizer Ernst
Ciba-Geigy Corporation
Gallagher Richard J.
Groeger Theodore O.
Kolodny Joseph G.
Maitner John J.
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