Process for preparing nitriles

Details Process for preparing nitriles Process for preparing nitriles

1987-12-21

1990-03-13

Brust, Joseph P.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

544204, 546228, 548341, 549474, 549548, 558312, 558313, C07D30346, C07D21382, C07C12010

Patent

active

049084526

ABSTRACT:
A facile and mild process for the preparation of nitriles from reagent sensitive primary carboxamides is described. The process utilizes a (carboxysulfamoyl)ammonium hydroxide compound as the dehydrating agent. It is useful for preparing nitriles which have present other groups which are sensitive to the more conventional methods of dehydration or to other methods of nitrile synthesis. Some novel nitriles prepared by the new method are also described.

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