Substituted-aza-cytosine compounds and anti-viral uses thereof

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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544194, 544211, C07D25110, A61K 3153

Patent

active

045017441

ABSTRACT:
Nucleoside analogues having a ring-open structure, of general formula: ##STR1## where R and R' may be hydrogen, silyl groups, substituted alkyl groups, benzyl groups and the like, and X is an optionally substituted pyrimidine or triazine base, exhibit anti-viral activities e.g. against herpes simplex virus and cytomegalo-virus at non-toxic levels.

REFERENCES:
patent: 4171431 (1979-10-01), Skulnick
patent: 4347360 (1982-08-01), Oglivie

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