Pyridyl substituted benzothiazole compounds which have useful ph

Details Pyridyl substituted benzothiazole compounds which have useful ph Pyridyl substituted benzothiazole compounds which have useful ph

1992-03-31

1994-04-05

Rotman, Alan L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546270, C07D27762, A61K 3141

Patent

active

053005180

ABSTRACT:
A benzothiazole derivative or a pharmacologically acceptable salt thereof which is useful as a preventive or therapeutic agent for diseases on which functions of suppressing leukotrienes and thromboxanes production are effective.
A benzothiazole derivative represented by the following general formula (I): ##STR1## wherein R.sup.1 and R.sup.3 are either the same or different and represents a hydrogen atom, a lower alkyl group or a lower alkoxy group; R.sup.4 represents a group represented by the formula --(CH.sub.x)--.sub.q wherein q is a integer of from 1 to 4;

REFERENCES:
patent: 1931077 (1933-10-01), Lubs et al.
patent: 4873346 (1989-10-01), Anderson
Journal of Organic Chemistry, vol. 35, No. 12, (1970) pp. 4103-4108 P. T. S. Lau et al.
Journal of Medicinal Chemistry, vol. 25, No. 6, (1982), pp. 654-657 Peter Ulrich et al.
European Search Report (2), Jun. 19, 1992.

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