Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1995-10-26
1998-03-31
Ketter, James
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
4351723, 43525233, 4353201, 530413, 536 234, C12Q 168, C12N 121, C12N 1572
Patent
active
057337314
ABSTRACT:
A random peptide library constructed by transforming host cells with a collection of recombinant vectors that encode a fusion protein comprised of a DNA binding protein and a random peptide and also encode a binding site for the DNA binding protein can be used to screen for novel ligands. The screening method results in the formation of a complex comprising the fusion protein bound to a receptor through the random peptide ligand and to the recombinant DNA vector through the DNA binding protein.
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Pluckthun and Ge,
Cull Millard G.
Gates Christian M.
Miller Jeff F.
Schatz Peter J.
Stemmer Willem Peter Christiaan
Affymax Technologies N.V.
Ketter James
Liebeschuetz Joe
Stevens Lauren L.
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