Imidazolidinone prostaglandins, compositions and use

Details Imidazolidinone prostaglandins, compositions and use Imidazolidinone prostaglandins, compositions and use

1983-10-05

1985-01-29

Ramsuer, Robert W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

548318, 548321, A61K 31415, C07D23302

Patent

active

044965770

ABSTRACT:
This invention relates to novel imidazolidinone prostaglandin compounds of the formula ##STR1## and the pharmaceutically acceptable salts thereof, wherein R.sup.1 and R.sup.2 are independently hydrogen or alkyl of 1 to 4 carbons; R.sup.3 is hydrogen or methyl; and R4 is --(CH.sub.2).sub.n CH.sub.3 wherein n is 3-7, cycloalkyl of 5-7 carbons, a substituent of the formula ##STR2## wherein R.sup.5 is hydrogen, alkyl of 1 to 4 carbons, alkoxy of 1 to 4 carbons, halo or trifluoromethyl. These compounds are inhibitors of blood platelet aggregation.

REFERENCES:
patent: 2430006 (1947-11-01), Duschinsky

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