Substituted alkyl amine derivatives of 6,11-dihydro-11-oxodibenz

Details Substituted alkyl amine derivatives of 6,11-dihydro-11-oxodibenz Substituted alkyl amine derivatives of 6,11-dihydro-11-oxodibenz

1986-06-18

1988-06-14

Hollrah, Glennon H.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

544375, 546 20, 546196, 546199, 549354, A61K 31335, C07D31312

Patent

active

047512385

ABSTRACT:
This invention relates to substituted alkyl amine derivatives of 6,11-dihydro-11-oxodibenz[b,e]oxepins of the formula: ##STR1## where X is hydrogen, halogen, lower alkoxy, lower alkyl, nitro, hydroxyl and CF.sub.3 ; R is H, and lower alkyl, R.sub.1 is CH.sub.3 SO.sub.3 and ##STR2## where R.sub.2 and R.sub.3 are the same of different and are hydrogen, lower alkyl, mesyl (CH.sub.3 SO.sub.2 --), and cycloalkyl loweralkyl; ##STR3## and the pharmaceutically acceptable acid addition salts thereof.

REFERENCES:
patent: 4107322 (1978-08-01), McFadden et al.
patent: 4117152 (1978-09-01), McFadden et al.

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