Device and method for measuring solubility and for performing ti

Details Device and method for measuring solubility and for performing ti Device and method for measuring solubility and for performing ti

1998-01-05

1999-12-21

Soderquist, Arlen

Chemistry: analytical and immunological testing

Including sample preparation

Liberation or purification of sample or separation of...

436178, 436163, 436164, 422 58, 422 81, 422 99, 422100, 422101, 422103, G01N 110, G01N 3100

Patent

active

060048220

ABSTRACT:
Described is a device and method for facilitating the determination of the solubility and dissolution properties of chemical compounds in various solvents. The device uses submilliliter quantities of a solvent and correspondingly small amounts of the chemical compound. The device enables solubility measurements to be made on small amounts of chemical compounds, and enables multiple sampling for generating dissolution profiles. The device includes a housing having first chamber in fluid communication with a second chamber. A pump is provided to force alternatingly the solvent from one chamber to another. A filter located between, and in fluid communication with, the first and second chambers allows flow of a solution of the solvent and the chemical compound between the chambers, and the filter prevents the passage of undissolved compound. The device may also be used for titration studies of submilliliter quantities of solutions or suspensions.

REFERENCES:
patent: 2946486 (1960-07-01), Gilmont
patent: 4086062 (1978-04-01), Hach
patent: 4335638 (1982-06-01), Smolen
patent: 4743570 (1988-05-01), Lamont, Jr.
patent: 5045284 (1991-09-01), Smith et al.
patent: 5156811 (1992-10-01), White
patent: 5240680 (1993-08-01), Zuckermann et al.
patent: 5364595 (1994-11-01), Smith
patent: 5496523 (1996-03-01), Gazit et al.
patent: 5552325 (1996-09-01), Nochumson et al.
patent: 5603900 (1997-02-01), Clark et al.
patent: 5635358 (1997-06-01), Wilding et al.
patent: 5711917 (1998-01-01), Juranas et al.
patent: 5719052 (1998-02-01), Ito et al.

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