Pyrrolo-pyridine derivatives and therapeutic compositions contai

Details Pyrrolo-pyridine derivatives and therapeutic compositions contai Pyrrolo-pyridine derivatives and therapeutic compositions contai

1991-05-31

1992-12-01

Dentz, Bernard

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546113, A61K 31435, C07D47104

Patent

active

051680980

ABSTRACT:
The invention relates to pyrrolo-pyridine derivatives of the formula: ##STR1## wherein R represents a phenyl group, optionally substituted by one or more of various groups and therapeutically acceptable salts of these compounds, to a preparation process of the same comprising reacting, in an inert atmosphere and in a protic solvent, the 2-methyl 3-hydroxy 4,5-diboromomethyl pyridine, on a stoichiometric excess of the compound of the formula NH.sub.2 -R.
The invention relates also to therapeutic compositions containing said derivatives as active ingredient.
The compounds according to the invention have antiallergic activity.

REFERENCES:
patent: 2767191 (1956-10-01), Wright, Jr. et al.
patent: 4206117 (1980-06-01), Von Phillipsborn et al.
Koruncev et al., Farm. Glas., 39(9), pp. 265-274 (1983); Chemical Abstracts, 101(9): 72638r (1983).

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