Human S1-5 ECMP-like protein

Details Human S1-5 ECMP-like protein Human S1-5 ECMP-like protein

1997-12-01

1999-12-21

Hutzell, Paula K.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

4353201, 435325, 435455, 536 231, C12Q 168, C12N 1500, C12N 500, C07H 2102

Patent

active

060047534

ABSTRACT:
The invention provides a human S1-5 ECMP-like protein (SELP) and polynucleotides which identify and encode SELP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of SELP.

REFERENCES:
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Taipale, J. and J. Keski-Oja, "Growth factors in the extracellular matrix", FASEB J., 11: 51-59 (1997).
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Lecka-Czernik, B. et al., "An Overexpressed Gene Transcript in Senescent and Quiescent Human Fibroblasts Encoding a Novel Protein in the Epidermal Growth Factor-Like Repeat Family Stimulates DNA Synthesis", Mol. Cell. Biol. 15: 120-128 (1995).
Lecka-Czernik, B. et al., (Direct Submission), GenBank Sequence Database (Accession U03877), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894, (GI 458227; GI 458228) Apr. 30, 1995.
Chiquet-Ehrismann, R. et al., "Tenascin: an Extracellular Matrix Protein Involved in Tissue Interactions during Fetal Development and Oncogenesis", Cell, 47: 131-139 (1986).

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