Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1992-10-14
1994-08-23
Lee, Lester L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514 19, 530330, 530331, A61K 3700, A61K 3702, C07K 500, C07K 700
Patent
active
053407989
ABSTRACT:
The present invention comprises fibrinogen receptor antagonist compounds, compositions containing them and methods for using them to inhibit fibrinogen binding to blood platelets. Compounds of the invention have the following formula ##STR1## wherein Z is ##STR2## X is COOH, CH.sub.2 SH or SH; R.sup.1 is Y--R.sup.3, wherein R.sup.3 is alkyl and Y is amino, pyridinyl, pyrimidinyl or piperidinyl;
REFERENCES:
patent: 4064255 (1977-12-01), Champseix et al.
patent: 5064814 (1991-11-01), Klein et al.
Nutt Ruth F.
Veber Daniel F.
Lee Lester L.
Matukaitis Paul D.
Merck & Co. , Inc.
Parr Richard S.
Salata C. A.
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