Fibrinogen receptor antagonists

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

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Details

514 19, 530330, 530331, A61K 3700, A61K 3702, C07K 500, C07K 700

Patent

active

053407989

ABSTRACT:
The present invention comprises fibrinogen receptor antagonist compounds, compositions containing them and methods for using them to inhibit fibrinogen binding to blood platelets. Compounds of the invention have the following formula ##STR1## wherein Z is ##STR2## X is COOH, CH.sub.2 SH or SH; R.sup.1 is Y--R.sup.3, wherein R.sup.3 is alkyl and Y is amino, pyridinyl, pyrimidinyl or piperidinyl;

REFERENCES:
patent: 4064255 (1977-12-01), Champseix et al.
patent: 5064814 (1991-11-01), Klein et al.

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