Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – In an organic compound
Patent
1997-05-30
1999-12-21
Shah, Mukund J.
Drug, bio-affecting and body treating compositions
Radionuclide or intended radionuclide containing; adjuvant...
In an organic compound
424 185, 424 961, 540121, 540122, 540145, A61K 5100, A61B 800, C07D48722, C09B 4704
Patent
active
060045302
ABSTRACT:
The present invention refers to a process for the preparation of an activated metallo-porphyrin derivative and to novel activated metallo-porphyrin derivatives obtainable by said process. Further, the present invention refers to conjugates of metallo-porphyrins with molecules having at least one primary amino group, especially biomolecules. The conjugates are used in a procedure for the detection of a biological substance, especially in an immunoassay or a nucleic acid hybridization assay.
REFERENCES:
patent: 4375972 (1983-03-01), Forgione et al.
patent: 4877872 (1989-10-01), Morgan et al.
Yu et al, Analytical Biochemistry, vol. 219, pp. 109-114, (1994) Universal Phosphorescence Immunoassay.
De Haas Richard Robert
Sagner Gregor
Tanke Hans
Van Gijlswijk Rob
Roche Diagnostics GmbH
Shah Mukund J.
Truong Tamthom N.
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