Oxazolyl, isoxazolyl, triazolyl and thiadiazolyl alkyl bisamidin

Details Oxazolyl, isoxazolyl, triazolyl and thiadiazolyl alkyl bisamidin Oxazolyl, isoxazolyl, triazolyl and thiadiazolyl alkyl bisamidin

1981-03-27

1983-02-08

Jiles, Henry R.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

424269, 548134, 548135, 548136, 548138, 548141, 548225, 548226, 548227, 548228, 548229, 548230, 548232, 548233, 548235, 548236, 548243, 548244, 548245, 548246, 548247, 548249, 548263, 548264, 548265, 548266, 548269, 548142, A61K 3141, A61K 3142, C07D24908, C07D26108, C07D26332, C07D28510, C07D28512

Patent

active

043729630

ABSTRACT:
Bisamidines carrying one unsaturated nitrogen heterocyclo-containing substituent, representative of which i; 1-[N'-(2-(5-methyl-4-imidazolyl)methylthio)ethyl)guanidino]-8-[N'-methylgu anidino]octane, are histamine H.sub.2 -antagonists.

REFERENCES:
patent: 4034101 (1977-07-01), Durant et al.
patent: 4062967 (1977-12-01), Durant et al.

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