Process for synthesis of coenzyme Q compounds

Details Process for synthesis of coenzyme Q compounds Process for synthesis of coenzyme Q compounds

1976-09-22

1977-12-13

Garner, Vivian

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260462C, 260462R, 260613D, C07C 4973, C07F 504

Patent

active

040628795

ABSTRACT:
A process for synthesizing 2,3-dimethoxy-5-methyl-6-substituted-1,4-benzoquinones having the formula: ##STR1## wherein R is ##STR2## in which n is an integer of 0 to 9, and A and B are hydrogens or taken together form a valence bond,
In which 2-methyl-4,5,6-trimethoxyphenol is reacted with boric acid or a reactive derivative thereof to obtain a 2-methyl-4,5,6-trimethoxyphenol ester of boric acid, reacting the resulting ester with an n-prenol or iso-prenol having the formula: ##STR3## wherein R is as defined above, OR A REACTIVE DERIVATIVE OF SAID N- OR ISO-PRENOL, IN THE PRESENCE OF A SILICA-ALUMINA COMPOUND, TO OBTAIN A 2-METHYL-3-SUBSTITUTED-4,5,6-TRIMETHOXYPHENOL ESTER OF BORIC ACID, AND HYDROLYZING THE THUS-OBTAINED ESTER AND TREATING THE RESULTING 2-METHYL-3-SUBSTITUTED 4,5,6-TRIMETHOXYPHENOL HAVING THE FORMULA: ##STR4## wherein R is as defined above, with an oxidant.

REFERENCES:
patent: 3068295 (1962-12-01), Folker et al.
patent: 3896153 (1975-07-01), Sato et al.

Affiliated with

Also associated with

Rating

Process for synthesis of coenzyme Q compounds does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for synthesis of coenzyme Q compounds, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for synthesis of coenzyme Q compounds will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-488886